Enjoy This Hudson, MA Hotel's Unique Location Located just off I-495 and I-290, the Holiday Inn Express® Hotel Boston - Marlboro offers a unique location among area accommodations. Just minutes from local corporate headquarters and the Massachusetts Turnpike, our hotel is also near Worcester, Framingham and Boston . This 100% non-smoking property is one of the best Marlboro, MA area hotels you can find. Because business travelers visit the Marlboro area so often, we have been named a Preferred Hotel by many nearby corporations, including Intel, IBM, Cisco, HP, Lowes and Fidelity. .